Program & Speakers > Program

See more about our invited speakers and session chairs.

Download the most up-to-date provisional program here.

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Tuesday, 15 October 2024

12:30 – 16:30  Registration
14:00 – 14:15 Opening Remarks 
14:15 – 16:10

Vitiligo, hair graying & other acquired pigmentary disorders

14:15 – 14:40 From translational data to clinical results: the crucial need for combination approaches to treat vitiligo Thierry Passeron
14:40 – 14:55 XPC-deficient Xenopus embryos: an in vivo model system for studying the mechanisms underlying pigmentary abnormalities in XPC patients Federica Papaccio
14:55 – 15:10 IGF/Insulin defective signalling at cellular level correlates to metabolic syndrome markers in vitiligo patients Joudi El Mir
15:10 – 15:30 UVB stress triggers hair greying: unveiling the Dicer-LEF/B-catenin pathway's role in melanocyte dysfunction Lionel Larue
15:30 – 15:45 Vitiligo auto-immune response upon oxidative stress-related mitochondrial DNA release opens up new therapeutic strategies Meri Tulic
15:45 – 16:10 The skin immune memory response in vitiligo Katia Boniface
16:10 – 16:40 Refreshments 
16:40 – 18:20 

Cutaneous mosaicism and cell-cell interactions

16:40 – 17:05 Crosstalk between tumor cells and their microenvironment in melanoma disease progression and therapy response Lukas Sommer
17:05 – 17:20 A new mosaic syndrome with linear skin hypopigmentation is associated with a GNA13 variant activating the RHOA/ROCK pathway and altering the cytoskeleton, cell morphology and melanosome transfer Pierre Vabres
17:20 – 17:35 Targeting GRPR for sex-hormone dependent cancer after E-cadherin loss Zackie Aktary
17:35 – 17:50 Anti-melanoma gene and protein expression in dermal sheath fibroblasts from hair follicles in Recessive Dystrophic Epidermolysis Bullosa (RDEB) scalp Joanna Stefan
17:50 – 18:15 Epidermal-melanin units of haired human skin: remarkable life-affirming partnerships on our UVR-drenched planet Desmond Tobin
18:15 – 19:15

Keynote Lecture : What separates a melanocyte from a melanoma?

Prof. Richard M. White, MD/PhD (Ludwig Institute for Cancer Research, Univ. of Oxford, UK)

19.20 – 20:30 Welcome reception
   

Wednesday, 16 October 2024

8:00 – 14:30  Registration
8:30 – 10:20 Melanosome trafficking, cell biology & melanin biochemistry
8:30 – 8:55 Physicochemical properties of melanin obtained from human induced pluripotent stem cell-derived melanocytes Michal Sarna
8:55 – 9:10 From pigment capture to intracellular positioning and photoprotection in keratinocytes Cédric Delevoye
9:10 – 9:25 Genetic and biochemical control over crystal formation in pigment cells Dvir Gur
9:25 – 9:40 Structural insights into pink-eyed dilution protein (Oca2) Shahram Mesdaghi
9:40 – 9:55 Unraveling UVA1-induced photo modifications of eumelanin and pheomelanin in human skin: insights into pigment darkening Sandra Del Bino-Nokin
9:55 – 10:20 Regulation of melanin secretion, transfer and processing in skin pigmentation Duarte Barral
10:20 – 10:50 Refreshments
10:50 – 13:00

Melanocyte development & extracutaneous pigmentation

10:50 – 11:15 (Online) Nerve-dependent origin of melanocytes beyond skin: evolutionary and pathological implications Igor Adameyko
11:15 – 11:30 Unraveling the ultrastructure and metabolome of unique pigment cells in the zebrafish fin Yael Noy
11:30 – 11:45 Eye melanosomes: understanding activity patterns in extant and ancient mammals Beatriz Carazo Del Hoyo
11:45 – 12:00 A deep dive into the anatomical distribution and geometry of melanosomes in fish Daniel Cirtina
12:00 – 12:15 Melanin-synthesizing cells in muscle: inflammatory changes in the Atlantic salmon (Salmo salar) Håvard Bjørgen
12:15 – 12:40 Single-cell, spatial multiomics, and system probing decode complete gene regulatory network underlying cranial neural crest fate decisions Tatjana Sauka-Spengler
12:40 – 13:00 Flash talk session #1: Poster teasers
13:00 – 14:30  POSTER SESSION #1 – Lunch
14:30 – 16:00

Melanocytic nevi: clinical and mechanistic facets

14:30 – 14:55 Transcriptional and metabolic cellular heterogeneity in melanoma residual disease E. Elizabeth Patton
14:55 – 15:10 Deconvoluted methylation profiles discriminate between closely related melanocytic nevi Daniel Aldea
15:10 – 15:25 Telomeres in the senescence of human acquired naevi Dot Bennett
15:25 – 15:40 Hedgehog signalling inhibition by SMO inhibitors in melanoma cells reveals a potential value for a new therapeutic strategy Barbara Bellei
15:40 – 16:05 RNA therapy for congenital melanocytic naevi Veronica Kinsler
16:05 – 16:35 Refreshments 
16:35 – 18:45

Melanomagenesis and metastasis (+uveal, acral, mucosal & juvenile melanoma)

16:35 – 17:00 (Online)   Chris Marine
17:00 – 17:25 Investigating the mechanisms of melanoma dissemination using zebrafish Julien Ablain
17:25 – 17:50 Increasing evidence for the application of FAK1 inhibitors in melanoma therapy Daniela De Zio
17:50 – 18:05 LKB1-SIK2 loss drives uveal melanoma proliferation and hypersensitivity to SLC8A1 and ROS inhibition Thomas Strub
18:05 – 18:20 Microenvironment-driven adaptation mechanisms in Melanoma: 3D Bioprinting and Tyrosine-induced phenotype switching Ahmed Najem
18:20 – 18:45 Stress adaptation in melanoma: the role of NRF2 Svenja Meierjohann
   

Thursday, 17 October 2024

8:00 – 13:30  Registration
8:30 – 10:15

Technological advances in melanoma detection and biomarkers

8:30 – 8:55 Single-cell molecular and functional landscapes of metastatic melanoma converge on clinically actionable features Mitch Levesque
8:55 – 9:10 e-DAM: An e-Delphi study to inform the clinical utility of AMBLor : a novel prognostic biomarker for early-stage cutaneous malignant melanoma Krishna Ravulapalli
9:10 – 9:35 Optimizing Drug Delivery for More Effective Melanoma Metastasis Treatment Luisa Lanfrancone
9:35 – 9:50 Melanoma macrophage and extracellular matrix transitions during the therapy-tolerant state Andrew White
9:50 – 10:15 Understanding molecular processes in tumor dormancy, metastasis and therapy Anja Bosserhoff
10:15 – 10:45 Refreshments 
10:45 – 12:30

(Epi+)genetics, post-transcriptional regulation

10:45 – 11:10 MITF directly regulates the expression of CDH1 but indirectly regulates CDH2 through SETDB2 and chromatin modifications Eirikur Steingrimmson
11:10 – 11:35 Contribution of lncRNAs to the generation of drug-tolerant persister cells Eleonora Leucci
11:35 – 11:50 Role of circRNAs to control gene expression program and cell plasticity associated with BRAFi resistance in melanoma Sebastien Corre
11:50 – 12:05 Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma Najla El Hachem
12:05 – 12:30 tRNA modifications: a new vulnerability in melanoma Pierre Close
12:30 – 13:00  Flash talk session #2: Poster teasers
13:00 – 14:30  POSTER SESSION #2 – Lunch
14:30 – 16:30

Albinism and other hereditary pigmentary disorders

14:30 – 14:55 Making sense of the genetic heterogeneity of albinism Lluis Montoliu
14:55 – 15:10 Role of ciliopathy-associated protein TMEM138 in skin pigmentation Brice Magne
15:10 – 15:35 Phenotyping of albinism Fanny Morice-Picard
15:35 – 15:50 Unraveling Griscelli's syndrome hypopigmentation using an in vitro model Joao Charneca
15:50 – 16:05 Oculocutaneous albinism type 2 (OCA2) in Cameroon and in sub-Saharan Africa: a 50-year-long-odyssey Robert Aquaron
16:05 – 16:30 Non-coding variants involved in the diagnosis of albinism Benoît Arveiler
16:30 – 17:00 Refreshments 
17:00 – 18:00 ESPCR General Assembly
19:30 – Conference dinner
   

Friday, 18 October 2024

8:30 – 11:40

Innovations in therapy for pigment cell diseases

8:30 – 8:55 Modelling systemic immunity in adoptive T cell therapy of melanoma Michael Holzel
8:55 – 9:20 Investigating new therapeutic approaches to combat metastatic melanoma Marie-Dominique Galibert
9:20 – 9:35 Investigating new therapeutic approaches to combat metastatic melanoma Jacques Rouanet
9:35 – 9:50 Impact of EGFR-TKI on Skin Pigmentation and Its Therapeutic Potential for Hypopigmented Skin Disorders Yang Lingli
9:50 – 10:05 Targeting Prohibitins and CRAF: A Promising Therapeutic Strategy for Melanoma Serena Sabbah
10:05 – 10:40 Refreshments 
10:40 – 11:05 The effect of melanosome systemic injection Carmit Levy
11:05 – 11:30 Melatonin-boosted efficacy of targeted therapy of human melanoma Konrad Kleszczynski
11:30 – 11:40 Presentation of the ESPCR PRIZE
11:40 – 12:40

ESPCR Award Lecture, sponsored by ESPCR

Skin pigment: from birth in melanocytes to demise in keratinocytes

Prof. Miguel Seabra, MD/PhD (Principal Investigator at NOVA Medical School, Lisbon, Portugal)

 Concluding Remarks

12:40 End of ESPCR 2024 annual meeting
14:00 – 17:30 

MELCAYA trainee meeting (English)

Rencontres avec des associations françaises de patients (en français)

French patient advocacy group breakout meetings (in French)

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