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Program & Speakers > Program
See more about our invited speakers and session chairs.
Download the most up-to-date provisional program here.
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Jump to: Wednesday Thursday Friday
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Tuesday, 15 October 2024 |
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| 12:30 – 16:30 | Registration | |
| 14:00 – 14:15 | Opening Remarks | |
| 14:15 – 16:10 |
Vitiligo, hair graying & other acquired pigmentary disorders |
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| 14:15 – 14:40 | From translational data to clinical results: the crucial need for combination approaches to treat vitiligo | Thierry Passeron |
| 14:40 – 14:55 | XPC-deficient Xenopus embryos: an in vivo model system for studying the mechanisms underlying pigmentary abnormalities in XPC patients | Federica Papaccio |
| 14:55 – 15:10 | IGF/Insulin defective signalling at cellular level correlates to metabolic syndrome markers in vitiligo patients | Joudi El Mir |
| 15:10 – 15:30 | UVB stress triggers hair greying: unveiling the Dicer-LEF/B-catenin pathway's role in melanocyte dysfunction | Lionel Larue |
| 15:30 – 15:45 | Vitiligo auto-immune response upon oxidative stress-related mitochondrial DNA release opens up new therapeutic strategies | Meri Tulic |
| 15:45 – 16:10 | The skin immune memory response in vitiligo | Katia Boniface |
| 16:10 – 16:40 | Refreshments | |
| 16:40 – 18:20 |
Cutaneous mosaicism and cell-cell interactions |
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| 16:40 – 17:05 | Crosstalk between tumor cells and their microenvironment in melanoma disease progression and therapy response | Lukas Sommer |
| 17:05 – 17:20 | A new mosaic syndrome with linear skin hypopigmentation is associated with a GNA13 variant activating the RHOA/ROCK pathway and altering the cytoskeleton, cell morphology and melanosome transfer | Pierre Vabres |
| 17:20 – 17:35 | Targeting GRPR for sex-hormone dependent cancer after E-cadherin loss | Zackie Aktary |
| 17:35 – 17:50 | Anti-melanoma gene and protein expression in dermal sheath fibroblasts from hair follicles in Recessive Dystrophic Epidermolysis Bullosa (RDEB) scalp | Joanna Stefan |
| 17:50 – 18:15 | Epidermal-melanin units of haired human skin: remarkable life-affirming partnerships on our UVR-drenched planet | Desmond Tobin |
| 18:15 – 19:15 |
Keynote Lecture : What separates a melanocyte from a melanoma? Prof. Richard M. White, MD/PhD (Ludwig Institute for Cancer Research, Univ. of Oxford, UK) |
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| 19.20 – 20:30 | Welcome reception | |
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Wednesday, 16 October 2024 |
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| 8:00 – 14:30 | Registration | |
| 8:30 – 10:20 | Melanosome trafficking, cell biology & melanin biochemistry | |
| 8:30 – 8:55 | Physicochemical properties of melanin obtained from human induced pluripotent stem cell-derived melanocytes | Michal Sarna |
| 8:55 – 9:10 | From pigment capture to intracellular positioning and photoprotection in keratinocytes | Cédric Delevoye |
| 9:10 – 9:25 | Genetic and biochemical control over crystal formation in pigment cells | Dvir Gur |
| 9:25 – 9:40 | Structural insights into pink-eyed dilution protein (Oca2) | Shahram Mesdaghi |
| 9:40 – 9:55 | Unraveling UVA1-induced photo modifications of eumelanin and pheomelanin in human skin: insights into pigment darkening | Sandra Del Bino-Nokin |
| 9:55 – 10:20 | Regulation of melanin secretion, transfer and processing in skin pigmentation | Duarte Barral |
| 10:20 – 10:50 | Refreshments | |
| 10:50 – 13:00 |
Melanocyte development & extracutaneous pigmentation |
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| 10:50 – 11:15 (Online) | Nerve-dependent origin of melanocytes beyond skin: evolutionary and pathological implications | Igor Adameyko |
| 11:15 – 11:30 | Unraveling the ultrastructure and metabolome of unique pigment cells in the zebrafish fin | Yael Noy |
| 11:30 – 11:45 | Eye melanosomes: understanding activity patterns in extant and ancient mammals | Beatriz Carazo Del Hoyo |
| 11:45 – 12:00 | A deep dive into the anatomical distribution and geometry of melanosomes in fish | Daniel Cirtina |
| 12:00 – 12:15 | Melanin-synthesizing cells in muscle: inflammatory changes in the Atlantic salmon (Salmo salar) | Håvard Bjørgen |
| 12:15 – 12:40 | Single-cell, spatial multiomics, and system probing decode complete gene regulatory network underlying cranial neural crest fate decisions | Tatjana Sauka-Spengler |
| 12:40 – 13:00 | Flash talk session #1: Poster teasers | |
| 13:00 – 14:30 | POSTER SESSION #1 – Lunch | |
| 14:30 – 16:00 |
Melanocytic nevi: clinical and mechanistic facets |
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| 14:30 – 14:55 | Transcriptional and metabolic cellular heterogeneity in melanoma residual disease | E. Elizabeth Patton |
| 14:55 – 15:10 | Deconvoluted methylation profiles discriminate between closely related melanocytic nevi | Daniel Aldea |
| 15:10 – 15:25 | Telomeres in the senescence of human acquired naevi | Dot Bennett |
| 15:25 – 15:40 | Hedgehog signalling inhibition by SMO inhibitors in melanoma cells reveals a potential value for a new therapeutic strategy | Barbara Bellei |
| 15:40 – 16:05 | RNA therapy for congenital melanocytic naevi | Veronica Kinsler |
| 16:05 – 16:35 | Refreshments | |
| 16:35 – 18:45 |
Melanomagenesis and metastasis (+uveal, acral, mucosal & juvenile melanoma) |
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| 16:35 – 17:00 (Online) | Chris Marine | |
| 17:00 – 17:25 | Investigating the mechanisms of melanoma dissemination using zebrafish | Julien Ablain |
| 17:25 – 17:50 | Increasing evidence for the application of FAK1 inhibitors in melanoma therapy | Daniela De Zio |
| 17:50 – 18:05 | LKB1-SIK2 loss drives uveal melanoma proliferation and hypersensitivity to SLC8A1 and ROS inhibition | Thomas Strub |
| 18:05 – 18:20 | Microenvironment-driven adaptation mechanisms in Melanoma: 3D Bioprinting and Tyrosine-induced phenotype switching | Ahmed Najem |
| 18:20 – 18:45 | Stress adaptation in melanoma: the role of NRF2 | Svenja Meierjohann |
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Thursday, 17 October 2024 |
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| 8:00 – 13:30 | Registration | |
| 8:30 – 10:15 |
Technological advances in melanoma detection and biomarkers |
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| 8:30 – 8:55 | Single-cell molecular and functional landscapes of metastatic melanoma converge on clinically actionable features | Mitch Levesque |
| 8:55 – 9:10 | e-DAM: An e-Delphi study to inform the clinical utility of AMBLor : a novel prognostic biomarker for early-stage cutaneous malignant melanoma | Krishna Ravulapalli |
| 9:10 – 9:35 | Optimizing Drug Delivery for More Effective Melanoma Metastasis Treatment | Luisa Lanfrancone |
| 9:35 – 9:50 | Melanoma macrophage and extracellular matrix transitions during the therapy-tolerant state | Andrew White |
| 9:50 – 10:15 | Understanding molecular processes in tumor dormancy, metastasis and therapy | Anja Bosserhoff |
| 10:15 – 10:45 | Refreshments | |
| 10:45 – 12:30 |
(Epi+)genetics, post-transcriptional regulation |
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| 10:45 – 11:10 | MITF directly regulates the expression of CDH1 but indirectly regulates CDH2 through SETDB2 and chromatin modifications | Eirikur Steingrimmson |
| 11:10 – 11:35 | Contribution of lncRNAs to the generation of drug-tolerant persister cells | Eleonora Leucci |
| 11:35 – 11:50 | Role of circRNAs to control gene expression program and cell plasticity associated with BRAFi resistance in melanoma | Sebastien Corre |
| 11:50 – 12:05 | Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma | Najla El Hachem |
| 12:05 – 12:30 | tRNA modifications: a new vulnerability in melanoma | Pierre Close |
| 12:30 – 13:00 | Flash talk session #2: Poster teasers | |
| 13:00 – 14:30 | POSTER SESSION #2 – Lunch | |
| 14:30 – 16:30 |
Albinism and other hereditary pigmentary disorders |
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| 14:30 – 14:55 | Making sense of the genetic heterogeneity of albinism | Lluis Montoliu |
| 14:55 – 15:10 | Role of ciliopathy-associated protein TMEM138 in skin pigmentation | Brice Magne |
| 15:10 – 15:35 | Phenotyping of albinism | Fanny Morice-Picard |
| 15:35 – 15:50 | Unraveling Griscelli's syndrome hypopigmentation using an in vitro model | Joao Charneca |
| 15:50 – 16:05 | Oculocutaneous albinism type 2 (OCA2) in Cameroon and in sub-Saharan Africa: a 50-year-long-odyssey | Robert Aquaron |
| 16:05 – 16:30 | Non-coding variants involved in the diagnosis of albinism | Benoît Arveiler |
| 16:30 – 17:00 | Refreshments | |
| 17:00 – 18:00 | ESPCR General Assembly | |
| 19:30 – | Conference dinner | |
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Friday, 18 October 2024 |
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| 8:30 – 11:40 |
Innovations in therapy for pigment cell diseases |
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| 8:30 – 8:55 | Modelling systemic immunity in adoptive T cell therapy of melanoma | Michael Holzel |
| 8:55 – 9:20 | Investigating new therapeutic approaches to combat metastatic melanoma | Marie-Dominique Galibert |
| 9:20 – 9:35 | Investigating new therapeutic approaches to combat metastatic melanoma | Jacques Rouanet |
| 9:35 – 9:50 | Impact of EGFR-TKI on Skin Pigmentation and Its Therapeutic Potential for Hypopigmented Skin Disorders | Yang Lingli |
| 9:50 – 10:05 | Targeting Prohibitins and CRAF: A Promising Therapeutic Strategy for Melanoma | Serena Sabbah |
| 10:05 – 10:40 | Refreshments | |
| 10:40 – 11:05 | The effect of melanosome systemic injection | Carmit Levy |
| 11:05 – 11:30 | Melatonin-boosted efficacy of targeted therapy of human melanoma | Konrad Kleszczynski |
| 11:30 – 11:40 | Presentation of the ESPCR PRIZE | |
| 11:40 – 12:40 |
ESPCR Award Lecture, sponsored by ESPCR Skin pigment: from birth in melanocytes to demise in keratinocytes Prof. Miguel Seabra, MD/PhD (Principal Investigator at NOVA Medical School, Lisbon, Portugal) |
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Concluding Remarks |
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| 12:40 | End of ESPCR 2024 annual meeting | |
| 14:00 – 17:30 |
MELCAYA trainee meeting (English) Rencontres avec des associations françaises de patients (en français) French patient advocacy group breakout meetings (in French) |
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